婴儿胃肠炎与虫害病毒抗原的分泌有关
R Yolken1, E Dubovi, F Leister
1Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
Lancet (London, England)
|March 11, 1989
概括
在患有不明原因胃肠炎的幼儿的便中检测到虫病毒抗原. 这一发现表明,虫病毒可能是儿童腹疾病的原因,经常伴有呼吸道症状.
科学领域:
- 病毒学 病毒学
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
背景情况:
- 幼儿的胃肠炎是一个重大的公共卫生挑战.
- 许多胃肠炎病例的病因仍未确定,尽管对常见的肠道病原体进行了测试.
研究的目的:
- 调查虫病毒在未知来源的儿科胃肠炎中的潜在作用.
- 为了比较Pestivirus相关的胃肠炎与其他腹疾病的临床表现.
主要方法:
- 来自患有胃肠炎的2岁以下儿童的便样本使用基于单克隆抗体的免疫试验测试了虫病毒抗原.
- 对照组包括没有腹的儿童和感染轮状病毒的儿童.
主要成果:
- 在128例无法解释的胃肠炎中,在30例中检测到虫病毒抗原.
- 在没有腹的儿童 (1/28) 和感染轮状病毒的儿童 (1/31) 中,虫病毒感染不常见.
- 与虫病毒分泌相关的胃肠炎显示出更高的呼吸道炎症症状的患病率.
结论:
- 鼠疫病毒是幼儿胃肠炎的潜在致病原体,特别是当其他肠道病原体未被确定时.
- 鼠疫病毒相关的胃肠炎可能会出现与呼吸道感染重叠的症状.
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