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RNA聚合酶II-Mediator核心启动复合物的结构

C Plaschka1, L Larivière2, L Wenzeck2

  • 1Max Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany.

Nature
|February 6, 2015
PubMed
概括

研究人员重建了核心调解器 (cMed) 综合体,并确定其与RNA聚合酶II (Pol II) 结合的结构. 这揭示了Mediator如何与Pol II相互作用,以调节基因转录启动.

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