血小板在37摄氏度进行短暂的输血前化有好处
R E Hutchinson1, K D Kunkel, M J Schell
1Department of Pathology, St Jude Children's Research Hospital, Memphis, Tennessee.
Lancet (London, England)
|May 6, 1989
概括
短时间将存储的血小板度加热到37°C,持续1小时,可提高儿童的输血效率. 与未加热的血小板相比,加热的血小板在输血后表现出更好的形态和更高的纠正血小板计数 (CCI).
科学领域:
- 血液学 血液学 血液学
- 输血医学 输血医学
- 儿科瘤学 儿科瘤学
背景情况:
- 血小板输血对于治疗儿科患者的血小板缺血至关重要,因为血小板缺血通常是化疗或无塑性贫血的结果.
- 血小板缩剂的标准储存条件可能会影响其输血后的疗效.
- 优化血小板的储存和制备对于最大限度地提高治疗效益至关重要.
研究的目的:
- 评估短暂升温对儿童患者储存血小板度的疗效的影响.
- 为了评估血小板形态的变化和经过输血后的血小板计数增量 (CCI) 的纠正,加热的血小板与未加热的血小板相比.
主要方法:
- 一项随机研究涉及15名患有稳定血小板缺血的儿科患者.
- 血小板缩物被分为两组:一个被加热到37°C1小时,另一个保持在室温.
- 每个患者都得到了一个加热和一个未加热的血小板袋,顺序输血.
主要成果:
- 温暖的血小板囊显著改善了血小板形态 (p = 0.0001).
- 经过校正的血小板计数增量 (CCI) 在输血后1小时 (p = 0.014) 和2小时 (p = 0.006) 显着更高,对于温暖的血小板.
- 这项研究表明,随着变暖协议的实施,输血效率得到了提高.
结论:
- 在输血之前,在室温下存储的血小板缩物短时间加热至37°C,持续1小时,可提高其在儿科患者的疗效.
- 这种加热方法导致输血后循环的血小板数量增加.
- 温暖储存的血小板是一种简单而有效的策略,可以提高患有血小板衰竭的儿童的输血结果.
相关概念视频
Blood Transfusion and Agglutination
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...


