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在DNA纳米技术. 编程与DNA链位移的体相位过渡

W Benjamin Rogers¹, Vinothan N Manoharan²

¹School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA.

Science (New York, N.Y.)

|February 7, 2015

概括

接种DNA的纳米粒子提供了对晶体结构和相位行为的可编程控制. 这项研究证明了使用DNA链位移编程完整相位图,从而实现了诸如回流融化之类的新型行为.

科学领域:

材料科学材料科学材料科学
纳米技术纳米技术
生物物理学的生物物理.

背景情况:

接种DNA的纳米粒子作为可编程的原子等价物,形成晶体.
它们的可编程性仅限于平衡水晶结构.

研究的目的:

将DNA移植纳米颗粒的可编程性概括为它们的完全温度依赖相位图.
探索超越简单晶体结构的新型相位行为.

主要方法:

在缓冲溶液中利用DNA链位移反应.
引入可溶性DNA链以与移植链竞争.

主要成果:

演示了完整相位图的编程,而不仅仅是晶体结构.
实现了独特的相位行为,包括广泛的气体-固体共存和反融化.
仅使用两个位移反应,展示了不同晶体相之间的可逆过渡.

结论:

接种DNA纳米颗粒的可编程性扩展到复杂的相位行为.
DNA链位移为设计体相图提供了一种多功能工具.
这种方法为创造具有可调节性质的先进材料打开了新的可能性.

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