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表达方式分析. 单细胞的组合标记用于基因表达细胞计.

H Christina Fan1, Glenn K Fu1, Stephen P A Fodor2

  • 1Cellular Research, Inc., 3183 Porter Drive, Palo Alto, CA 94304, USA.

Science (New York, N.Y.)
|February 7, 2015
PubMed
概括

这项研究引入了一种简单的基因表达细胞测量方法,使用下一代测序和随机条形编码. 该技术能够对数千个单细胞进行数字基因表达分析,揭示了对人类造血系统的洞察力.

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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