在白血病中进行自身移植
1Department of Medicine, UCLA Center for the Health Sciences 90024.
Lancet (London, England)
|August 5, 1989
概括
骨髓自体移植在早期缓解的白血病患者中显示出有前途. 然而,由于有限的数据,它们在晚期疾病中的有效性和与其他治疗方法的比较仍然不确定.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 移植医学 移植医学
背景情况:
- 骨髓自移植 (自动-HSCT) 用于治疗白血病.
- 在第一和第二次缓解的白血病患者中观察到有利的结果.
研究的目的:
- 为了评估自移植在晚期白血病的疗效.
- 为了比较自身移植与化疗和异种移植.
主要方法:
- 对自身移植结果现有数据的分析.
- 确定当前研究的局限性,包括缺乏前性试验和混因素.
主要成果:
- 自体移植在晚期白血病病例中表现出有限的成功.
- 关于自身移植对其他疗法的优越性存在不确定性.
结论:
- 自动移植的挑战包括消除白血病,缺少移植对白血病效应,以及潜在的恶性细胞再注入.
- 需要进一步的前性试验来澄清自身移植在白血病治疗中的作用.
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