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合成二极体ADP-ribose及其结构与人类的多分子ADP-ribose) 糖酶

Michael J Lambrecht1, Matthew Brichacek1, Eva Barkauskaite2

  • 1†Department of Chemistry, Roger Adams Laboratory, University of Illinois, 600 South Mathews, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|February 24, 2015
PubMed
概括

在结构研究中,化学合成的ADP-核糖二聚体提供同质的多ADP-核糖 (PAR). 这一突破使人类PARG的第一个共晶结构成为可能,进步了我们对细胞过程中PAR蛋白相互作用的理解.

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