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下丘脑POMC神经元促进大麻素诱导的食

Marco Koch1, Luis Varela2, Jae Geun Kim2

  • 11] Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA [2] Institute of Anatomy, University of Leipzig, 04103 Leipzig, Germany.

Nature
|February 25, 2015
PubMed
概括

大麻素受体1 (CB1R) 的激活令人惊地增加了下丘脑的亲opiomelanocortin (POMC) 神经元活动,促进食. 在大麻素驱动的养中,这种意想不到的POMC神经元作用涉及β-endorphin释放和线粒体适应.

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