发展中国家肝脏疾病中的超声波和光学扫描. 一个追溯调查调查
B Maharaj1, I G Bhoora, A Patel
1Department of Experimental and Clinical Pharmacology, University of Natal Medical School, Durban, South Africa.
Lancet (London, England)
|October 7, 1989
概括
肝超声学 (US) 和光学扫描 (SG) 在检测扩散性肝病的准确性有限. 虽然对焦点病变有效,但区分原因可能需要活检.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 诊断成像 诊断成像 诊断成像
- 医疗技术 医疗技术 医学技术
背景情况:
- 准确检测肝病至关重要,特别是在发展中国家.
- 肝超声学 (US) 和光学扫描 (SG) 是常见的成像方法.
- 之前的研究表明,这些技术的有效性各不相同.
研究的目的:
- 评估肝超声波 (美国) 和光学扫描 (SG) 在发达国家检测肝病的诊断价值.
- 评估US和SG在区分正常肝脏和患病肝脏的准确性,以及区分焦点和扩散性肝脏疾病的准确性.
- 确定US和SG识别肝病特定原因的能力.
主要方法:
- 追溯对425个US扫描和304个SG扫描的回顾,来自有焦点或扩散性肝病或正常肝脏的患者.
- 对检测焦点和扩散性肝病的灵敏度和特异性的分析.
- 对特定疾病的诊断准确性的评估,如阿米巴肝,肝细胞癌和转移性癌.
主要成果:
- 对于区分正常肝脏和患病肝脏的整体准确性是低的 (美国:68%,SG:74%).
- 对焦点肝病的敏感性很高 (美国:88%,SG:92%),但对于扩散性疾病的敏感性很低 (美国:27%,SG:54%).
- 对于这两种技术都观察到高特异性 (91-96%),但美国显示空间占用病变的特征重叠,影响最终诊断的准确性 (例如,29%的肝细胞癌).
结论:
- 肝脏US和SG在检测扩散性肝病时表现出有限的准确性,并且无法确定其原因.
- 建议在怀疑扩散性细胞性肝病时进行活检.
- 虽然对焦点疾病有效,但由于占用空间的病变之间的特征重叠,美国可能需要活检或志向进行最终诊断.
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