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Updated: Apr 16, 2026

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神经元CRTC-1通过一种甲基荷胺信号来控制系统性线粒体代谢和寿命

Kristopher Burkewitz1, Ianessa Morantte1, Heather J M Weir1

  • 1Department of Genetics and Complex Diseases, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.

Cell
|February 28, 2015
PubMed
概括

神经CRTC-1对线粒体功能的重编程通过将能量感应与副作用分离来促进长寿. 外周代谢的这种中央调节取代了局部衰老机制,这表明准中央能量感知可能会增强健康的衰老.

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