针对急性损伤的自动化电子警报:单盲,并行组,随机对照试验
F Perry Wilson1, Michael Shashaty2, Jeffrey Testani1
1Yale University School of Medicine, Program of Applied Translational Research, New Haven, CT, USA.
Lancet (London, England)
|March 2, 2015
概括
对急性损伤 (AKI) 的电子警报系统并没有改善住院患者的临床结果. 早期发现AKI对于及时干预和改善患者预后至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床信息学 临床信息学
- 医疗保健技术 技术 医疗保健 技术
背景情况:
- 急性损伤 (AKI) 在早期往往没有被发现,错过了及时治疗的机会.
- 针对AKI的有效干预措施在早期启动时是最有益的.
- 这项研究调查了自动化警报系统对AKI严重程度和患者结局的影响.
研究的目的:
- 评估急性损伤 (AKI) 的自动电子警报是否可以降低损伤严重程度并改善住院患者的临床结果.
- 评估AKI预警系统在现实医院环境中的有效性.
主要方法:
- 一个随机对照试验,涉及1期或更大的AKI的成年患者.
- 患者被分配到AKI电子警报系统或通常的护理.
- 主要结局是肌素变化,透析和7天内死亡的复合结果.
主要成果:
- 在综合结果 (p=0.88) 中,AKI警报系统与通常的护理没有显著差异.
- 7天后,研究小组之间没有观察到肌素变化,透析率或死亡率的显著差异.
- 随机分层的子组分析也显示没有显著的改善.
结论:
- 对急性损伤 (AKI) 的自动电子警报系统没有证明住院患者的临床结果有所改善.
- 这些发现表明,目前的电子警报系统可能不足以改变该人口中AKI的进程.
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