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Updated: Apr 16, 2026

Method for Efficient Refolding and Purification of Chemoreceptor Ligand Binding Domain
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Published on: December 12, 2017

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调整细胞因子受体信号通过重新定位二元体几何与代用子的替代子

Ignacio Moraga1, Gerlinde Wernig2, Stephan Wilmes3

  • 1Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305-5345, USA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305-5345, USA.

Cell
|March 3, 2015
PubMed
概括

研究人员探索了改变受体二元结构如何影响细胞信号传递. 他们发现,工程Diabodies可以控制受体活性,提供一种新的策略来抵消癌症驱动突变.

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