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Strand-Specific Analysis of Proteins at Replicating DNA Strands by Enrichment and Sequencing of Protein-Associated Nascent DNA Method
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调节的真核DNA复制起源与纯化蛋白质一起燃烧

Joseph T P Yeeles1, Tom D Deegan1, Agnieszka Janska1

  • 1Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms EN6 3LD, UK.

Nature
|March 6, 2015
PubMed
概括

研究人员使用42种蛋白质重建了真核细胞DNA复制启动. 这个过程受到循环素依赖激酶 (CDK) 和Dbf4依赖激酶 (DDK) 的严格调节,以确保精确的基因组重复.

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