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Updated: Apr 16, 2026

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
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结构生物学 结构生物学. 化学激素识别和激活病毒G蛋白结合受体的结构基础

John S Burg1, Jessica R Ingram2, A J Venkatakrishnan3

  • 1Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|March 7, 2015
PubMed
概括

研究人员可视化了与人类化学因子结合的病毒化学因子受体 (GPCR) 的结构. 这揭示了病毒GPCRs如何在没有外部信号的情况下保持活跃,影响免疫逃避策略.

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