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潘特拉辛3通过P-选择蛋白/矩阵金属蛋白酶-1通路诱导血管内皮功能障碍

Albino Carrizzo1, Paola Lenzi1, Claudio Procaccini1

  • 1From IRCCS Neuromed, Pozzilli, Italy (A.C., A.D., F.B., M.A., M.M., F.F., C.V.); University of Pisa, Department of Human Morphology and Applied Biology, Italy (P.L., F.F.); Laboratory of Immunology, Institute of Experimental Endocrinology and Oncology, National Research Council of Italy (IEOS-CNR), c/o Department of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", Napoli, Italy; (C.P., V.G.); University of Salerno, Department of Pharmaceutical Sciences, Fisciano (Salerno), Italy (G.A.); University of Salerno, Medicine and Surgery, Baronissi (Salerno), Italy (G.A., P.R., A.A.P., G.M., C.V.); Hypertension Research Center and Department of Advanced Biomedical Sciences (D.G.C., B.T.) and Department of Translational Medical Sciences (R.I.), University of Naples "Federico II", Napoli, Italy; University of Pavia, Department of Industrial and Information Engineering, Italy (A. Malovini); Department of Science and Technology, University of Sannio, Benevento, Italy (L.F.); Pathology Unit, "Istituto Nazionale Tumori, IRCCS, Fondazione Pascale," Naples, Italy (V.G.); and IRCCS Multimedica, Milan, Italy (A.A.P., G.M.).

Circulation
|March 10, 2015
PubMed
概括

潘特拉辛3 (PTX3) 通过损害氧化信号,直接导致血管功能障碍和高血压. 升高的PTX3,P-selectin和矩阵金属蛋白酶-1可以预测高血压中的血管问题.

关键词:
生物标志物生物标志物它们的内皮质 (endothelium).这种高血压是高血压.氧化氧化是什么?

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