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子的最佳性是mRNA稳定性的一个主要决定因素

Vladimir Presnyak1, Najwa Alhusaini1, Ying-Hsin Chen1

  • 1Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, OH 44106, USA.

Cell
|March 14, 2015
PubMed
概括

使者RNA (mRNA) 的稳定性受到密码子最佳性的显著影响. 使用最佳编码子提高mRNA稳定性,而非最佳编码子导致更快的降解,影响基因表达.

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