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Updated: Apr 16, 2026

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
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Published on: January 20, 2023

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基于人类TRAP1晶体结构的线粒体向Hsp90抑制剂的开发

Changwook Lee, Hye-Kyung Park, Hanbin Jeong

  • 1∥New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 701-310, Korea.

Journal of the American Chemical Society
|March 19, 2015
PubMed
概括

研究人员开发了一种新的线粒体TRAP1抑制剂SMTIN-P01,以更有效地向癌细胞. 这种新药与现有的Hsp90抑制剂相比,通过在线粒体中专门积累,显示出更好的细胞毒性.

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