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铁性作为p53介导的活动在瘤抑制过程中

Le Jiang1, Ning Kon1, Tongyuan Li1

  • 1Institute for Cancer Genetics, College of Physicians &Surgeons, Columbia University 1130 St Nicholas Ave, New York, New York 10032, USA.

Nature
|March 25, 2015
PubMed
概括

瘤抑制剂p53通过抑制囊的吸收来调节细胞代谢,促进铁亡 (一种细胞死亡形式). 这一途径对于瘤抑制至关重要,独立于传统的p53功能.

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