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Updated: Apr 15, 2026

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在体内结构性印记解码RNA调节机制

Robert C Spitale1, Ryan A Flynn1, Qiangfeng Cliff Zhang1

  • 1Howard Hughes Medical Institute and Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA.

Nature
|March 25, 2015
PubMed
概括

研究人员在体内开发了选择性2'-基化和分析实验 (icSHAPE),以绘制活细胞中的RNA结构. 这种方法揭示了动态RNA结构,对于基因表达和RNA-蛋白相互作用至关重要.

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