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核酸结合性寡聚化域2受体在血小板中表达,并增强血小板激活和血栓形成

Si Zhang1, Shenghui Zhang1, Liang Hu1

  • 1From Key Laboratory of Molecular Medicine, Ministry of Education, and Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai, China (Si Zhang, Shenghui Zhang, L.H., L.Z., J.Y., L.C., Z.D.); Department of Internal Medicine, and Institute of Liver Disease, Fudan University Zhongshan Hospital, Shanghai, China (R.X.); Thoracic Oncology Research Laboratory, University of Pennsylvania, Philadelphia, (G.C.); Department of Internal Medicine, University of Kansas School of Medicine, Wichita (J.S.M.); and Department of Physiology and Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA (S.P.K.).

Circulation
|April 1, 2015
PubMed
概括

核酸结合寡聚化域2 (NOD2) 在血小板中表达,增强血小板激活,血栓形成和炎症,特别是在感染期间. 这项研究揭示了NOD2信号与血栓事件之间的新联系.

关键词:
血小板是血液中的血小板.通过基因激活的蛋白质激酶.核酸结合的寡合化领域2受体相互作用蛋白质氨酸-三氨酸激酶2的受体.血栓形成的原因是血栓形成.

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