在高血压的高血压
Neil R Poulter1, Dorairaj Prabhakaran2, Mark Caulfield3
1International Centre for Circulatory Health, Imperial College London, London, UK.
Lancet (London, England)
|April 3, 2015
概括
高血压是全球主要的健康问题. 有效的预防和优化高血压管理,包括负担得起的多药疗法,至关重要,特别是在发展中国家.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 遗传学 遗传学 是一个
背景情况:
- 血压升高 (高血压) 是全球疾病负担和死亡率的主要贡献者.
- 全球高血压患病率预计将在未来十年显著上升.
- 目前对高血压的遗传洞察力对整体血压管理的影响很小.
研究的目的:
- 突出全球迫切需要预防策略和优化高血压管理.
- 强调解决环境决定因素和实施基于证据的疗法的重要性.
- 探索组合药物治疗和种族特异性治疗评估的潜力.
主要方法:
- 审查与高血压相关的全球疾病负担和死亡率数据.
- 对目前对高血压原因的遗传研究进行分析.
- 评估多药高血压治疗方案的疗效和资源影响.
主要成果:
- 高血压仍然是全球死亡率和疾病的主要原因.
- 环境因素和治疗实施对于血压控制至关重要.
- 三种药物组合可以实现高高血压控制率 (约. 90%) 如果价格负担得起且易于获得.
结论:
- 需要紧急实施预防策略和优化高血压管理,特别是在不发达国家.
- 环境干预和有效的治疗实施是控制血压的关键.
- 负担得起,可访问的组合疗法和特定种族的治疗策略对于最佳的高血压控制至关重要.
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