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排除T细胞,免疫特权和瘤微环境

Johanna A Joyce1, Douglas T Fearon2

  • 1Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. joycej@mskcc.org dfearon@cshl.edu.

Science (New York, N.Y.)
|April 4, 2015
PubMed
概括

瘤微环境可以保护癌细胞免受T细胞的影响,阻碍有效的免疫疗法. 流体细胞可能会排除T细胞,从而产生免疫特权. 克服这一障碍是成功治疗癌症的关键.

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