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eIF3针对细胞增殖信使RNA进行翻译激活或抑制

Amy S Y Lee1, Philip J Kranzusch2, Jamie H D Cate3

  • 11] Department of Molecular &Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA [2] Center for RNA Systems Biology, University of California, Berkeley, Berkeley, California 94720, USA.

Nature
|April 8, 2015
PubMed
概括

细胞启动因子3 (eIF3) 通过结合特定的信使RNA来控制蛋白质合成. 这种对细胞生长至关重要的相互作用可以激活或抑制翻译,为癌症提供新的治疗点.

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