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Updated: Apr 15, 2026

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on: November 2, 2018

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通过KPC1介导的NF-κB1p105到p50的全方位化和蛋白质体处理限制了瘤的生长

Yelena Kravtsova-Ivantsiv1, Inna Shomer1, Victoria Cohen-Kaplan1

  • 1The David and Janet Polak Cancer and Vascular Biology Research Center, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 31096, Israel.

Cell
|April 11, 2015
PubMed
概括

研究人员确定KPC1是调节NF-κB1处理的泛素酶. 这一发现揭示了一种通过平衡转录因子活性来控制细胞生长和瘤抑制的新机制.

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Purification of Ubiquitinated p53 Proteins from Mammalian Cells

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