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替代3' UTRs作为支架来调节膜蛋白局部化的作用

Binyamin D Berkovits1, Christine Mayr1

  • 1Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, New York 10065, USA.

Nature
|April 22, 2015
PubMed
概括

替代多基化 (ApA) 生成不同的3'未翻译区域 (3' UTRs),控制膜蛋白的定位和功能. 这种机制扩大了蛋白质组的多样性,而不改变蛋白质序列,影响细胞表面表达.

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