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Updated: Apr 14, 2026

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes
07:59

A High Throughput MHC II Binding Assay for Quantitative Analysis of Peptide Epitopes

Published on: March 25, 2014

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突变MHCII类表位驱动治疗性免疫反应对癌症的治疗

Sebastian Kreiter1, Mathias Vormehr2, Niels van de Roemer2

  • 1TRON - Translational Oncology at the University Medical Center of Johannes Gutenberg University, Freiligrathstrasse 12, 55131 Mainz, Germany.

Nature
|April 23, 2015
PubMed
概括

针对瘤特异性突变的个性化癌症疫苗,特别是那些被CD4 ((+) T细胞识别的,显示出强烈的抗瘤活性. 这种方法利用生物信息选择和mRNA技术,为有效的个性化癌症免疫疗法提供了通用策略.

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