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HLA-DRB1单元类型与类风湿性关节炎严重程度,死亡率和治疗反应的关联

Sebastien Viatte1, Darren Plant2, Buhm Han3

  • 1Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, England.

JAMA
|April 29, 2015
PubMed
概括

特定的HLA-DRB1单元类型影响类风湿性关节炎 (RA) 的进展,增加放射性损伤和死亡率,同时改善对瘤死因子 (TNF) 抑制剂的反应.

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