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Updated: Jul 30, 2026

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通过结合性的细胞索引,通过多重单细胞对色素可访问性的分析

Darren A Cusanovich1, Riza Daza1, Andrew Adey2

  • 1University of Washington, Department of Genome Sciences, Seattle, WA, USA.

Science (New York, N.Y.)
|May 9, 2015
PubMed
概括

这项研究引入了一种可扩展的方法,用于数千个单细胞的表观基因组分析,克服了以前的局限性. 这种新技术可以进行详细的染色质可访问性映射,以推进细胞图谱项目.

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相关概念视频

Fixation and Sectioning01:03

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...