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口服类固醇治疗由于腰椎椎间盘的急性根基病变:一项随机临床试验

Harley Goldberg1, William Firtch2, Mark Tyburski3

  • 1Kaiser Permanente Northern California Spine Care Program, San Jose2Division of Research, Kaiser Permanente Northern California, Oakland.

JAMA
|May 20, 2015
PubMed
概括

口服普雷尼松在患有椎间盘的急性坐骨髓炎患者中改善了功能,但没有减少疼痛. 与安慰剂相比,这种短期的类固醇治疗导致了更多的不良事件.

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Herniated Intervertebral Disc l: Introduction01:29

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...