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Updated: Apr 11, 2026

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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细胞粘附. 细胞粘附. 机械应变会诱导依赖E-cadherin的Yap1和β-catenin激活,从而推动细胞循环的进入

Blair W Benham-Pyle1, Beth L Pruitt2, W James Nelson3

  • 1Program in Cancer Biology, Stanford University, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|May 30, 2015
PubMed
概括

机械应变通过Yap1和β-catenin通路触发细胞增殖. 在上皮细胞中,E-cadherin对于这些机械信号响应至关重要,调节组织发育.

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