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糖修饰调节了先天免疫受体Nod2的稳定性和功能

James E Melnyk1, Vishnu Mohanan1, Amy K Schaefer1

  • 1†Department of Chemistry and Biochemistry, and §Department of Biological Sciences, University of Delaware, Newark, Delaware 19716, United States.

Journal of the American Chemical Society
|June 3, 2015
PubMed
概括

修改peptidoglycan连接物稳定了Nod2受体,微调了天生的免疫反应. 研究人员开发了一种新型合成来调整连接体结构,从而调节Nod2激活的治疗潜力.

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