相关实验视频
Updated: Apr 10, 2026

07:42
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
84.5K
这是遗传学. 用破碎的染色体制造头部或尾部
1Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, 3584CG Utrecht, Netherlands. w.kloosterman@umcutrecht.nl.
概括
No abstract available in PubMed .
相关概念视频
Karyotyping
70.4K
Overview
70.4K
Karyotyping
12.1K
12.1K
Nondisjunction
10.1K
10.1K
Nondisjunction
5.9K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers. Nondisjunction is common during anaphase I or anaphase II of meiosis. Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
5.9K
Nondisjunction
83.8K
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
83.8K
Crossing Over
7.3K
Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I,...
7.3K

