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Light-driven Enzymatic Decarboxylation
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新的辅助因子支持通过1,3-双极循环添加的α,β不和酸脱碳化

Karl A P Payne1, Mark D White1, Karl Fisher1

  • 1Centre for Synthetic Biology of Fine and Speciality Chemicals, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK.

Nature
|June 18, 2015
PubMed
概括

菌Fdc1酶利用一种新型的先化黄素辅因子催化可逆芳香脱碳化. 这种反应机制涉及一种独特的酶性1,3-双极循环添加,为化学合成提供了新的途径.

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