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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
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Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

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传染病 传染病 传染病 传染病 设计者蛋白质产生强大的艾滋病毒防御能力

Jon Cohen

    Science (New York, N.Y.)
    |June 20, 2015
    PubMed
    概括

    No abstract available in PubMed .

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    Inhibitors of Viral Protein Synthesis01:30

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    Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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