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Updated: Apr 7, 2026

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

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曼德利酸和α-Phenylglycine的单选择性o-C-H功能化

Navid Dastbaravardeh1, Tetsuya Toba1, Marcus E Farmer1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|July 12, 2015
PubMed
概括

这项研究介绍了催化C-H功能化的新方法,用于曼德利酸和α-phenylglycine. 这些高效的协议使得化,化,乙氧化和化无需指导群体,从而保留了性中心.

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Just like β-keto acids—which upon thermal decarboxylation form ketones—β-dicarboxylic acids undergo decarboxylation to generate monocarboxylic acids with the liberation of carbon dioxide.
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