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两个美洲的创始人口的遗传证据
Pontus Skoglund1,2, Swapan Mallick1,2,3, Maria Cátira Bortolini4
1Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
Nature
|July 22, 2015
概括
遗传研究显示,一些亚马逊土著美国人与澳大利亚人有血统联系,这表明美洲的创始人多样化超出了以前的理解.
科学领域:
- 人口遗传学
- 人类的起源
- 古代DNA分析
背景情况:
- 之前的遗传研究表明美国原住民来自东北亚.
- 形态学研究表明,一些早期的美国骨与澳大利亚人有共同的特征,与东北亚的亲缘关系形成鲜明对比.
- 这表明美洲的人口可能比以前更复杂.
研究的目的:
- 使用全基因组数据调查美洲原住民的祖先起源.
- 澄清古今美洲原住民和其他全球人口之间的遗传关系.
- 评估美洲创始人的多样性.
主要方法:
- 对当今亚马逊原住民的全基因组数据进行分析.
- 将遗传特征与全球各种人口进行比较,包括澳大利亚土著,新几内亚人,安达曼岛民,欧亚人和古北美基因组.
- 研究的遗传混合物和祖先组成部分.
主要成果:
- 在一些亚马逊群体中发现了与原住民澳大利亚人,新几内亚人和安达曼岛民比现在的欧亚人或美洲原住民更密切相关的原住民.
- 这种独特的祖先签名在今天的北美和中美洲基本上不存在.
- 在12,600年前的克洛维斯相关基因组中也没有检测到这种特征.
结论:
- 这些发现表明美洲的创始人群体比以前所接受的多样化.
- 支持多个祖先血统对南美洲的人口贡献的假设.
- 突出古代DNA和基因组数据在解决复杂的人类迁徙历史中的重要性.
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