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Updated: Jan 14, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
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通过保持转化生长因子-β信号通路,Sirt7有助于心肌组织的修复

Satoshi Araki1, Yasuhiro Izumiya2, Taku Rokutanda1

  • 1From Departments of Cardiovascular Medicine (S.A., Y.I., T.R., S.H., Y.K., Y.O., H.O.) and Medical Biochemistry (T.S., T.Y., K.Y.), Graduate School of Medical Sciences, Kumamoto University, Japan; Department of Cardiac Development and Remodeling, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany (A.I., T.B., E.B.); Department of Cardiovascular Clinical and Translational Research, Kumamoto University Hospital, Japan (O.Y.); and Department of Medicine and Biological Science, Gunma University Graduate School of Medicine, Maebashi, Japan (N.K., M.K.).

Circulation
|July 24, 2015
PubMed
概括

Sirtuin 7 (Sirt7) 对心血管组织的修复至关重要. 由于影响纤维化和自,Sirt7的丧失会影响伤口愈合,并增加心脏破裂的风险.

关键词:
自食症纤维细胞转化生长因子β的受体其他伤口愈合

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