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来自脂蛋白和膜间细胞的自毒素促进大动脉膜的炎症和矿物化

Rihab Bouchareb1, Ablajan Mahmut1, Mohamed Jalloul Nsaibia1

  • 1From Laboratoire d'Études Moléculaires des Valvulopathies (LEMV), Groupe de Recherche en Valvulopathies (GRV), Quebec Heart and Lung Institute/Research Center, Department of Surgery (R.B., A.M., M.J.N., M.-C.B., J.-L.L., M.-H.L., F.H., P.M.), Department of Medicine (A.D., P.P., B.J.A., A.M.), Department of Pathology (C.C., S.T., S.P.), and Department of Molecular Medicine (Y.B.), Laval University, Québec, Canada; and Department of Chemistry and Biochemistry, University of Windsor, Ontario, Canada (C.A.S., R.R., M.L.K.).

Circulation
|July 31, 2015
PubMed
概括

脂蛋白 ((a) 将自毒素 (ATX) 运送到大动脉,在那里,ATX- lysophosphatidic 酸通过驱动炎症和矿化促进大动脉疾病 (CAVD),这表明了新的治疗点.

关键词:
欧盟国家安全委员会大动脉狭窄症,化大动脉狭窄症自动毒素甲状腺膜疾病脂肪蛋白 (a)脂肪蛋白质化酸化酸胆

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