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Updated: Jan 8, 2026

Environmental Modulations of the Number of Midbrain Dopamine Neurons in Adult Mice
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错误向的线粒体蛋白在细胞质中激活蛋白静态反应

Lidia Wrobel1, Ulrike Topf1, Piotr Bragoszewski1

  • 1International Institute of Molecular and Cell Biology, 02-109 Warsaw, Poland.

Nature
|August 7, 2015
PubMed
概括

线粒体蛋白质进口缺陷会触发细胞的保护性反应. 这种通过错误准蛋白质 (UPRam) 激活的未展开的蛋白质反应抑制了蛋白质合成,并激活了蛋白质组以清除错误定位的蛋白质.

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