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Updated: Apr 5, 2026

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
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在单个细胞中扩大基因

Zhe Liu1

  • 1Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA.

Cell
|August 16, 2015
PubMed
概括

研究人员开发了一种高通量成像位置映射平台 (HIPmap),用于单细胞中精确的3D基因映射. 他们发现DNA复制,而不是细胞分裂, 显著影响基因组定位.

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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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