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患有急性B型 (DeBakey III) 大动脉解剖的患者的结局:一个13年的单中心经验
Rana O Afifi1, Harleen K Sandhu1, Samuel S Leake1
1From the University of Texas Medical School at Houston and Memorial Hermann Heart & Vascular Institute, Houston.
Circulation
|August 26, 2015
概括
急性乙型大动脉解剖 (ATBAD) 的结果取决于并发症. 复杂的ATBAD患者的生存率较低,但不复杂的ATBAD也需要对晚期问题进行监测.
科学领域:
- 心血管外科
- 血管外科
- 大动脉疾病
背景情况:
- 动脉解剖是一种常见的动脉灾难.
- 在内血管时代,急性乙型大动脉解剖 (ATBAD) 的治疗正在发展.
研究的目的:
- 评估在13年内接受治疗的ATBAD患者的长期结果.
- 根据疾病状况 (复杂与无复杂) 和治疗方式进行比较.
主要方法:
- 对442名ATBAD患者 (2001 - 2014) 的回顾性评估.
- 将ATBAD分为复杂的 (破裂,扩张,疼痛,失血) 和不复杂的.
- 使用卡普兰-梅尔和描述性统计数据分析无干预和整体存活率.
主要成果:
- 60. 6% 的患者有无并发症的ATBAD (uATBAD),39. 4% 的患者有并发症的ATBAD (cATBAD).
- 在5年后无干预生存率为uATBAD的62. 7%,在cATBAD组中为42. 5%至47. 2%.
- 整体存活率与复杂表现有显著的关系.
结论:
- 早期和晚期的ATBAD结果受到并发症的存在的影响.
- 虽然uATBAD的早期存活率很好,但晚期并发症需要监测和潜在的干预措施.
- 需要进行进一步的前性试验,以优化uATBAD的治疗.
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