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Updated: Apr 4, 2026

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抑制DNA甲基化通过dRNA引起癌症的干扰反应,包括内源性逆转录病毒

Katherine B Chiappinelli1, Pamela L Strissel2, Alexis Desrichard3

  • 1Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21287, USA.

Cell
|August 29, 2015
PubMed
概括

DNA甲基转移酶抑制剂 (DNMTis) 通过病毒防御途径激活癌症免疫信号. 这会引发卵巢癌的亡,并使黑色素瘤对免疫疗法敏感, 这突显出一种新的治疗策略.

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