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Visualizing and Quantifying Endonuclease-Based Site-Specific DNA Damage
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病毒和细胞基因组激活不同的DNA损伤反应

Govind A Shah1, Clodagh C O'Shea1

  • 1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037-1002, USA.

Cell
|August 29, 2015
PubMed
概括

MRE11/RAD50/NBS1-ATM通路通过阻止病毒DNA复制来防御腺病毒. 这种局部反应与全球DNA损伤反应不同,可以防止病毒扩散而不会伤害细胞.

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