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Updated: Apr 4, 2026

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

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致癌RAB蛋白的鉴定

Douglas B Wheeler1, Roberto Zoncu2, David E Root3

  • 1Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA. Weill Cornell/Rockefeller University/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY 10021, USA. Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.

Science (New York, N.Y.)
|September 5, 2015
PubMed
概括

RAB35小瓜诺辛三酸酶 (GTPase) 调节PI3K/AKT通路. 在瘤中失调的RAB35激活了这种途径,促进了细胞的生存和转化.

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