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Updated: Apr 4, 2026

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
07:04

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

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黑色素瘤细胞内在的PD-1受体功能促进瘤生长

Sonja Kleffel1, Christian Posch2, Steven R Barthel1

  • 1Harvard Skin Disease Research Center, Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

Cell
|September 12, 2015
PubMed
概括

在黑色素瘤细胞的编程细胞死亡1 (PD-1) 驱动瘤生长,即使没有免疫细胞. 抑制这种内在的PD-1通道减缓了黑色素瘤的进展,这表明了新的治疗点.

关键词:
黑色素瘤美国其他类型S6 核糖体蛋白抗体封锁免疫检查点mTOR信号提供一个p-S6编程细胞死亡-1治疗方法

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