怀孕并发症和心血管疾病死亡:儿童健康和发育研究怀孕队列的50年随访
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在PubMed上查看摘要
概括
此摘要是机器生成的。孕期并发症如高血压和糖尿明显预测心血管疾病 (CVD) 的死亡. 这些情况的结合,以及早产, 确定女性患心血管疾病死亡的风险很高.
科学领域
- 生殖健康
- 心血管疾病流行病学
- 妇产科
背景情况
- 关于怀孕并发症如何预测心血管疾病 (CVD) 随着时间的推移而导致死亡的研究有限.
- 这项研究全面研究了多胎妊娠并发症与五十年内心血管疾病死亡率之间的联系.
研究的目的
- 调查各种妊娠并发症与心血管疾病 (CVD) 死亡风险之间的联系.
- 确定妊娠并发症的特定组合,表明心血管疾病死亡风险增加.
- 探索这种风险如何随着年龄的增长而演变.
主要方法
- 1959年至1967年的怀孕事件分析和14,062名妇女的心血管疾病死亡数据.
- 使用加利福尼亚生命统计和国家死亡指数来确定心血管疾病死亡.
- 检查的危险因素包括先前存在的高血压,血糖尿,孕前 (早期和晚期发病),以及血红蛋白下降.
主要成果
- 预先存在的高血压,血糖尿,晚期发作的孕前,以及血红蛋白下降是心血管疾病死亡的重要预测因素.
- 早期发生的孕前和早产或早产婴儿预测过早的心血管疾病死亡,风险取决于年龄.
- 结合过早分娩与出血或高血压,以及先前存在的高血压的孕前,导致心血管疾病死亡风险大幅增加 (4至7倍).
结论
- 妊娠并发症的特定组合,包括糖尿和血红蛋白下降,是高心血管疾病死亡风险的新预测因素.
- 妇产科医生可以利用这些已知的妊娠并发症来识别风险较高的妇女, 以早期预防心血管疾病.
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