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它们限制了HIV-1的感染性,并且被Nef

Yoshiko Usami1, Yuanfei Wu1, Heinrich G Göttlinger1

  • 1Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

Nature
|September 30, 2015
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) Nef蛋白和小鼠白血病病毒glycoGag通过阻止SERINC3和SERINC5蛋白质融入病毒细胞来降低病毒感染力. 这一发现为抗击艾滋病毒/艾滋病提供了潜在的策略.

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