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内体Vps34复合体的结构和灵活性揭示了其在膜上的功能的基础

Ksenia Rostislavleva1, Nicolas Soler1, Yohei Ohashi1

  • 1MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.

Science (New York, N.Y.)
|October 10, 2015
PubMed
概括

内体复合II (PIK3C3-CII) 的晶体结构显示其Y形和子单元相互作用. 这种复合物对膜交易至关重要,具有特定的Vps30循环,使膜酸化成为可能.

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