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在CRISPR-Cas适应性免疫过程中捕获外来DNA

James K Nuñez1, Lucas B Harrington1, Philip J Kranzusch1,2

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.

Nature
|October 28, 2015
PubMed
概括

细菌和古生物通过整合外来DNA来防御病毒使用CRISPR免疫力. 研究人员揭示了Cas1-Cas2酶复合物如何捕获DNA, 作为CRISPR位置结构的分子统治者.

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