关闭水龙头:通过积极发现病例和迅速有效治疗来阻止结核病的传播
Courtney M Yuen1, Farhana Amanullah2, Ashwin Dharmadhikari1
1Brigham and Women's Hospital, Boston, MA, USA.
Lancet (London, England)
|October 31, 2015
概括
阻止结核病的传播需要识别感染者并迅速开始治疗. 针对性积极发现病例的策略在高负担地区是有效的,可以显著降低结核病发病率.
科学领域:
- 公共卫生
- 流行病学
- 传染病控制
背景情况:
- 全球结核病 (TB) 流行需要停止传播以防止新的感染.
- 及时诊断和有效治疗对于使感染者变得非传染性至关重要.
- 结核病负担很高的地区往往因缺乏积极的病例发现而面临诊断和治疗的延迟.
研究的目的:
- 评估积极发现病例的策略对结核病传播的影响.
- 评估有针对性的活跃病例寻找在减少结核病发病率中的作用.
- 倡导将积极的病例调查纳入全面的结核病控制战略.
主要方法:
- 在高结核病负担的环境中,积极发现病例的有效性.
- 对案例发现对人口水平的影响进行数学建模预测的分析.
- 综合关于迅速和正确的治疗策略的证据.
主要成果:
- 在高结核病负担的环境中,各种积极的病例发现策略已被证明是有效的.
- 研究和建模表明,有针对性的活跃病例发现可以降低人口水平的结核病发病率.
- 有效的策略可确保及时诊断和正确治疗,使个体不具有传染性.
结论:
- 有针对性的活跃病例发现是控制全球结核病流行病的关键组成部分.
- 实施积极的病例调查可以大大降低结核病发病率.
- 将这些策略纳入更广泛的防治工作是阻止结核病传播的关键.
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